Véronique Gouverneur Research

Department of Chemistry University of Oxford


109 Hypoxia imaging Agents – bis(thiosemicarbazones) beyond the parent Cu(ATSM) 
R. Huting, V. Keersemans, M. Tredwell, M. Christlieb, V. Gouverneur, J. Dilworth
Nuclear Medicine and Biology 2010, 37(6), 695-696

108 Gold Catalysis and Fluorine
M. N. Hopkinson, A. D. Gee and V. Gouverneur
Isr. J. Chem. 2010, 50, 675-690

107 Gold-Catalyzed Cascade Cyclization-Oxidative Alkynylation of Allenoates
M. Hopkinson, J. Ross, G. Giuffredi, A. D. Gee and V. Gouverneur
Org. Lett. 2010, 12 (21), 4904-4907

106 Catalytic Enantioselective Synthesis of P-Stereogenic Compounds
J. S. Harvey, V. Gouverneur
Chem. Comm. 2010, 46, 7477-7485 (Feature Article)

105 Radiosynthesis and Evaluation of [18F]Selectfluor bis(triflate)
H. Teare, E.G. Robins, A. Kirjavainen, S. Forsback, G. Sandford, O. Solin, S. K. Luthra, V. Gouverneur
Angew. Chem. Int. Ed. 2010, 49, 6821-6824 HOT Paper

104 Gold-Catalyzed Diastereoselective Synthesis of α-Fluoroenones from Propargyl Acetates
Matthew N. Hopkinson, Guy T. Giuffredi, Antony D. Gee and Véronique Gouverneur
Synlett 2010, 18, 2737-2742

103 Bis(thiosemicarbazones) as bifunctional chelators for the room temperature labelling of peptides and proteins
R. Hueting, M. Christlieb, J. R Dilworth, E. García Garayoa, V. Gouverneur, M. W. Jones, V. Maes, R.Schibli, X. Sun, and D. A. Tourwé
Dalton Transactions 2010, 39, 3620-3632 HOT Paper

102 Synthesis and O-Phosphorylation of 3,3,4,4-Tetrafluoro-Aryl-C-Nucleoside Analogues
Laurent Bonnac, Sarah E. Lee, Guy T. Giuffredi, Lucy M. Elphick, Alexandra A. Anderson, Emma S. Child, David J. Mann and Véronique Gouverneur
Org. Biomol. Chem. 2010, 8, 1445-1454

101 Diastereoselective Synthesis of P-Stereogenic Heterocycles via Enyne Ring-Closing Metathesis
James Stephen Harvey, Guy T. Giuffredi and Veronique Gouverneur
Org. Lett. 2010, 12, 1236-1239

100 Catalytic activation of hydrogen, silicon, and fluorine by transition-metal complexes
Rauf W, Hazari A, Gouverneur V.
Pure and Applied Chemistry 2010, 82, 1415-1428

99 Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [F-18]FMISO as hypoxia-selective tracer for PET
Bejot R, Kersemans V, Kelly C, Carroll L, King R. C., Gouverneur, V.
Nuclear Medicine and Biology 2010 37, 565-575

98 Syntheses of Mono-, Di-, and Trifluorinated Styrenic Monomers
Walkowiak J, del Campo TM, Ameduri B, Gouverneur, V.
Synthesis 2010 11, 1883-1890

97 Orthogonal F-18 and Cu-64 labelling of functionalised bis(thiosemicarbazonato) complexes
L. Carroll, R. Bejot, R. Hueting, V. Gouverneur
Chem. Commun. 2010 46, 4052-4054 Cover

96 Gold-Catalyzed Intramolecular Oxidative Cross-Coupling of Nonactivated Arenes
M. N. Hopkinson, A. Tessier,A. Salisbury, V. Gouverneur
Chem. A Eur. Journal 2010 16, 4739-4743

95 Transition-Metal-Mediated Reactions for C(sp2)–F Bond Construction: the State of Play
J. M. Brown, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 8610-8614

94 A New departure in Fluorination Chemistry
V. Gouverneur
Science 2009 325, 1630-1631

93 Recent Progress in the use of Fluoroorganic Compounds in Pericyclic Reactions
Y-h. Lam, S. J. Stanway, V. Gouverneur
Tetrahedron 2009, 65 9905-9933

92 Electrophilic Fluorocyclization of Allyl Silanes
S. C. Wilkinson, O. Lozano, M. Schuler, M. Pacheco, R. Salmon, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 7083-7086

91 Oxidative Detagging of Fluorous Organosilanes
S. Boldon, J. E. Moore, V. Gouverneur
J. Fluor. Chem. 2009, 130, 1151-1156 (By Invitation - Issue to celebrate the International Conference on Fluorine Chemistry ’09, Kyoto)

90 Developments in Fluorocyclization Methodologies
S. C. Wilkinson, R. Salmon, V. Gouverneur
Future Med. Chem. 2009, 1 (5), 847-863 (Special Focus: Fluorine in Medicinal Chemistry - By Invitation)

89 Exploring the Roles of Protein Kinases Using Chemical Genetics
L. M. Elphick, S. E. Lee, A. A. Anderson, E. S. Child, L. Bonnac, V. Gouverneur, D. J. Mann
Future Med. Chem. 2009, 1 (7), 1233 (By Invitation)

88 A Quantitative Comparison of Wild Type and Gatekeeper Mutant Cdk2 for Chemical Genetic Studies with ATP Analogues
L. M. Elphick, S. E. Lee, E. S. Child, A. Prasad, C. Pignocchi, S. Thibaudeau, A. A. Anderson, L. Bonnac, V. Gouverneur, D. J. Mann
ChemBioChem. 2009, 10, 1519-1526

87 Synthesis and Reactivity of Novel g-Phosphate Modified ATP Analogues
S. E. Lee, L. M. Elphick, A. A. Anderson, E. S. Child, D. J. Mann, V. Gouverneur
Bio. Med. Chem. Lett.2009, 19, 3804-3807 (By Invitation)

86 Asymmetric de novo Synthesis of Fluorinated D-Glucitol and D-Mannitol Analogues
G. T. Giuffredi, S. Purser, M. Sawicki, A. L. Thompson, V. Gouverneur
Tetrahedron Asym. 2009, 20, 910-920 (By Invitation)

85 Phosphine-Catalysed Cyclisation of b-Hydroxy-,-Difluoroynones
M. Schuler, A. Monney, V. Gouverneur
Synlett 2009, 11, 1733-1736; highlighted in SYNFACTS (Issue 9, 964)

84 Palladium-Catalyzed Substitution of Allylic Fluorides
A. Hazari, V. Gouverneur, J. M. Brown
Angew. Chem. Int. Ed. 2009, 48, 1296-1299

83 Diels–Alder Exo-Selectivity in Terminal-Substituted Dienes and Dienophiles: Experimental Discoveries and Computational Explanations
Y-h. Lam, P. H-Y. Cheong, J. M. Blasco Mata, S. J. Stanway, V. Gouverneur, K. N. Houk
J. Am. Chem. Soc. 2009, 131, 1947-1957

82 Enantioselective Synthesis of P-Stereogenic Phosphinates and Phosphine Oxides by Mo-Catalyzed Asymmetric Ring-Closing Metathesis
J. S. Harvey, S. J. Malcolmson, K. S. Dunne, S. J. Meek, A. L. Thompson, R. R. Schrock, A. H. Hoveyda, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 762-766; highlighted in SYNFACTS (Issue 4, 397)

81 Fluorous Synthesis of 18F-Radiotracers with [18F] Fluoride ion: Nucleophilic Fluorination as the Detagging Process
R. Bejot, T. Fowler, L. Carroll, S. Boldon, J. E. Moore, J. Declerck, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 586-589

80 A Two-Directional Approach to Enantiopure 1,4-Difluoro-Cyclohexenes: Synthesis of Difluorinated Cyclitol Analogues
S. Purser, T. D. W. Claridge, B. Odell, P. R. Moore, V. Gouverneur
Org. Lett. 2008, 10, 4263-4266

79 Gold(I)-Catalyzed Alkoxyhalogenation of b-Hydroxy-a,a-Difluoroynones
M. Schuler, F. Silva, C. Bobbio, A. Tessier, V. Gouverneur
Angew. Chem. Int. Ed. 2008, 47, 7927-7930

78 Fluorous Synthesis of Allylic Fluorides: C–F bond Formation as the Detagging Process
S. Boldon, J. E. Moore, V. Gouverneur
Chem. Commun. 2008, 31, 3622-3624

77 The Chemistry of Propargylic and Allylic Fluorides
M. Pacheco, S.Purser, V. Gouverneur
Chem. Rev. 2008, 108, 1943-1981

76 First Examples of Molecularly Imprinted Nanogels with Aldolase Type I Activity 

D. Carboni, K. Flavin, A. Servant, V. Gouverneur, M. Resmini 
Chem. Eur. J. 2008, 14, 7059-7065

75 Stereospecific anti SE2' Fluorination of Allenylsilanes: Synthesis of Enantioenriched Propargylic Fluorides

L. Carroll, S. McCullough, T. Rees, T. D. W. Claridge, V. Gouverneur
Org. Biomol. Chem. 2008, 6, 1731-1733

74 Fluorine-Directed Diastereoselective Iodocyclisations

M. Tredwell, J. A. R. Luft, M. Schuler, K. Tenza, K. N. Houk, V. Gouverneur
Angew. Chem. Int. Ed. 2008, 47(2), 357-360 Selected by the Editor as a Hot Article.

73 Fluorine in Medicinal Chemistry
S. Purser, P. R. Moore, S. Swallow and V. Gouverneur
Chem. Soc. Rev. 2008 37, 320-330 (Tutorial Review)

72 Diastereoselective Fluorination of Silylated 1,2-Oxazines to Access Fluorinated N,O-Heterocycles
. Y.-h. Lam, M. N. Hopkinson, S. J. Stanway and V. Gouverneur
Synlett 2007, 19, 3022-3027

71 Single and Double Stereoselective Fluorination of (E)-Allylsilanes
M. Sawicki, A. Kwok, M. Tredwell and V. Gouverneur
Beilstein Journal of Organic Chemistry 2007, 3:34 . [Thematic Issue on Contemporary Organosilicon Chemistry] By Invitation.

70 A Concise Synthesis of Enantioenriched Fluorinated Carbocycles
Y.-h. Lam, C. Bobbio, I. R. Cooper, V. Gouverneur
Angew. Chem. Int. Ed. 2007, 46(27), 5106-5110. Highlighted as a Frontispiece and selected as a SYNFORM story.

69 Kinetics of Radical Copolymerisation of [1-(Fluoromethyl)vinyl]benzene with Chlorotrifluoroethylene 

G. Kostov, M. Tredwell, V. Gouverneur, B. Ameduri 
J. Poly. Sci. Part A: Polymer Chem., 2007, 45, 3843-3850

68 Using chemical genetics and ATP analogues to dissect protein kinase function
L. M. Elphick, S. E. Lee, V. Gouverneur, D. J. Mann
ACS Chem. Biol. 2007, 2(5), 299-314

67 Synthesis and Reactivity of [18F] N-Fluorobenzenesulfonimide 
H. Teare, E. G. Robins, E. Årstad, S. K. Luthra and V. Gouverneur
Chem. Commun. 2007, 23, 2330-2332 [Front Cover]

66 Highly Diastereoselective Electrophilic Fluorination of Cyclic Syn b-Hydroxysilanes 
S. Purser, C. Wilson, P. R. Moore, V. Gouverneur
Synlett 2007, 7, 1166-1168

65 A Convergent Approach for the Synthesis of fluorinated Sphingosine Analogues 
H. Teare, F. Huguet, M. Tredwell, S. Thibaudeau, S. K. Luthra, V. Gouverneur
Arkivoc 10, 232-244 2007 [commemorative Issue for Professor A. Krief] By Invitation.

64 Enantioselective Organocatalytic Aldol reaction of Ynones and its Synthetic Applications
F. Silva, M. Sawicki, V. Gouverneur
Org. Lett. 2006, 8(23) 5417-5419

63 Pd(II)-Catalysed CascadeWacker-Heck Reaction: Chemoselective Coupling of Two Electron Deficient Reactants
F. Silva, M. Reiter, R. Mills-Webb, M. Sawicki, D. Klär, N. Bensel, A. Wagner, V. Gouverneur
J. Org. Chem. 2006, 71, 8390-8394

62 Homometathesis and Cross-Metathesis Coupling of Phosphino-Borane Templates with Electron-rich and electron-Poor Olefins
K. S. Dunne, S. E. Lee, V. Gouverneur
J. Organometal. Chem. 2006, 691 (24-25), 5246-5259

61 Enantioselective Synthesis of a Key “A Ring” Intermediate for the preparation of 1-alpha-Fluoro Vitamin D3 Analogues
G. Giuffredi, C. Bobbio, V. Gouverneur
J. Org. Chem. 2006, 5361-5364

60 Synthesis and Synthetic Applications of Allylic monofluorides
M. Pacheco, V. Gouverneur
Chemistry Today 2006, 24, 12-16

59 Catalytic Asymmetric Fluorination
C. Bobbio and V. Gouverneur
Org. Biomol. Chem. 2006, 2065-2075 [Inside Cover]

58 Synthesis of Propargylic Fluorides from Allenylsilanes
L. Carroll, L. Garcia, M. C. Pacheco and V. Gouverneur
Chem. Commun. 2006, 39, 4113-4115

57 Sequential Desymmetrization-Fluorination: Enantioselective synthesis of fluorinated Cyclitols 
S. Purser, P. Moore and V. Gouverneur
Chemistry A European Journal 2006, 12(36), 9176-9185

56 Intramolecular Hetero-Michael Addition of -Hydroxyenones for the Preparation of Highly Substituted Tetrahydropyranones
M. Reiter, H. Turner, V. Gouverneur
Chemistry A European Journal 2006, 12(27), 7190-7203

55 Electrophilic Fluorination of Organosilanes
M. Tredwell, V. Gouverneur
Org. Biomol. Chem., 2006, 26-32 [Featured in Chemical Science]