Véronique Gouverneur Research

Department of Chemistry University of Oxford

 

191 Hydrochlorofluoromethylation of Unactivated Alkenes with Chlorofluoroacetic Acid
Meyer C, Hell S, Sap J, Misale A, Peschiulli A, Oehlrich D, Trabanco A, Gouverneur V
Invited contribution to the special issue in honour of Professor Steve Davies.
Tetrahedron 2019, DOI:10.1016/j.tet.2019.130679

 

 

190 Imaging of translocator protein upregulation is selective for pro-inflammatory polarised astrocytes and microglia
Pannell M, Economopoulos V, Wilson T, Kersemans V, Isenegger P, Larkin J, Smart S, Gilchrist S, Gouverneur V, Sibson N
GLIA 2019. DOI:10.1002/glia.23716

  

 189 In My Element: Fluorine
Gouverneur V
In My Element series celebrates the personal accounts from Chemistry-
A European Journal Editorial Board members for the 2019 International Year
of the Periodic Table.
Chem. Eur. J.  2019, 25, 7958- 7959. DOI:10.1002/chem.201902265

  

 188 Hydrodifluoromethylation of Alkenes with Difluoroacetic Acid
Meyer C, Hell S, Misale A, Trabanco A, Gouverneur V
Angew. Chem. Int. Ed. 2019, 58, 8828- 8833. DOI:10.1002/anie.201903801

  

187 The fluorination of C–H bonds: developments and perspectives
Szpera R, Moseley D, Smith L, Sterling A, Gouverneur V
Angew. Chem. Int. Ed. 2019, DOI:10.1002/anie.201814457

 

186 Synthesis of 18F-Difluoromethylarenes Using Aryl Boronic Acids, Ethyl bromofluoroacetate and [18F]Fluoride
Sap J, Wilson T, Kee C, Straathof N, Amende C, Mukherjee P, Zhang L, Genicot C, Gouverneur V
Chem. Sci. 2019, 10, 3237 - 3241. DOI: 10.1039/C8SC05096A

 

185 Hydrogen Bonding Phase-Transfer Catalysis with Potassium Fluoride: Enantioselective Synthesis of β-Fluoroamines
Pupo G, Vicini A, Ascough D, Ibba F, Christensen K, Thompson A , Brown J , Paton R, Gouverneur V
J. Am. Chem. Soc. 2019, 141, 2878–2883. DOI: 10.1021/jacs.8b12568

 

184 Synthesis and Reactivity of a-Cumyl Bromodifluoromethanesulfenate: Application to the Radiosynthesis of [18F]ArylSCF3
Wu J, Zhao Q, Wilson T, Verhoog S, Lu L, Gouverneur V and Shen Q
Angew. Chem. Int. Ed. 2019, 58, 1 – 6. DOI: 10.1002/anie.20181370

 

183 Data-mining the diaryl(thio)urea conformational landscape: Understanding the contrasting behavior of ureas and thioureas with quantum chemistry
Luchini G, Ascough D, Alegre-Requena J, Gouverneur V, Paton R
Special Issue Paper: Computational Chemistry in Organic Synthesis. Guest Editors: Dean Tantillo and John Wood
Tetrahedron 2019, 75, 697-702. DOI: 10.1016/j.tet.2018.12.033

  

182 Enantioselective rhodium-catalysed insertion of trifluorodiazoethanes into tin hydrides Hyde S, Veliks J, Ascough D, Szpera R, Paton R, Gouverneur V
Special Issue in honour of Prof Leon Ghosez
Tetrahedron 2019, 75, 17-25. DOI: 10.1016/j.tet.2018.11.022

 

181 PET Imaging of PARP Expression Using 18F-Olaparib
Wilson T, Xavier M, Knight J, Verhoog S, Torres J, Mosley M, Hopkins S, Wallington S, Allen P, Kersemans V, Hueting R, Smart S, Gouverneur V, Cornelissen B
J. Nucl. Med. 2019, 60, 504-510. DOI: 10.2967/jnumed.118.213223

 

180 Boron reagents for divergent radiochemistry
Wilson T, Cailly T, Gouverneur V
Chem Soc Rev2018, 47, 6990-7005. DOI: 10.1039/c8cs00499d

 

 

179 Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis
Pupo G, Ibba F, Ascough D, Vicini A, Ricci P, Christensen K, Pfeifer L, Morphy J, Brown J, Paton R, Gouverneur V
Science 2018, 360, 638-642. DOI: 10.1126/science.aar7941

 

 178 Highly Diastereoselective Synthesis of Trifluoromethyl Indolines by Interceptive Benzylic Decarboxylative Cycloaddition of Nonvinyl, Trifluoromethyl Benzoxazinanones with Sulfur Ylides under Palladium Catalysis
Punna N, Das P, Gouverneur V, Shibata N

Org. Lett. 2018, 20, 1526-1529. DOI: 10.1021/acs.orglett.8b00237

 

177 Controlled Single and Double Iodofluorination of Alkynes with DIH- and HF-Based Reagents
Pfeifer L, Gouverneur V

Org. Lett. 2018, 20, 1576-1579. DOI: 10.1021/acs.orglett.8b00321

 

176 Selective Radical Trifluoromethylation of Native Residues in Proteins
Imiołek M, Karunanithy G, Ng W, Baldwin A, Gouverneur V, Davis B
J. Am. Chem. Soc. 2018, 7, 1568-1571. DOI: 10.1021/jacs.7b10230

 

 

175 18F-Trifluoromethylation of Unmodified Peptides with 5-18F-(Trifluoromethyl)dibenzothiophenium Trifluoromethanesulfonate
Verhoog S, Kee C, Wang Y, Khotavivattana T, Wilson T, Kersemans V, Smart S, Tredwell M, Davis B, Gouverneur V
J. Am. Chem. Soc. 2018, 7, 1572-1575. DOI: 10.1021/jacs.7b10227

 

174 Synthesis, characterization, thermal and surface properties of co- and terpolymers based on fluorinated a-methylstyrenes and styrene
Walkowiak-Kulikowska J, Szwajca A, Gouverneur V, Ameduri B 
Polym. Chem-Uk 2017, 8, 6558-6569. DOI: 10.1039/C7PY01529A

 

173 De-Risking the Cu-Mediated 18F-Fluorination of Heterocyclic PET Radioligands
Taylor N, Emer E, Preshlock S, Schedler M, Tredwell M, Verhoog S, Mercier J, Genicot C, Gouverneur V
J. Am. Chem. Soc. 2017, 139, 8267-8276. DOI: 10.1021/jacs.7b03131

 

172 Synthesis and Reactivity of 18F-Labeled α,α-Difluoro-α-Aryloxyacetic Acids
Khotavivattana T, Calderwood S, Verhoog S, Pfeifer L, Preshlock S, Vasdev N, Collier T, Gouverneur V
Org. Lett. 2017, 19, 568-571. DOI: 10.1021/acs.orglett.6b03730

 

171 The Dual Role of Thiourea in the Thiotrifluoromethylation of Alkenes 
Ricci P, Khotavivattana T, Pfeifer L, Médebielle M, Morphy J, Gouverneur V 
Chem. Sci. 2017, 8, 1195-1199. DOI: 10.1039/C6SC02790C

 
 

170 Bridging the gaps in 18F PET tracer development 
Campbell M, Mercier J, Genicot C, Gouverneur V, Hooker J, Ritter T 
Nat. Chem.
2017, 9, 1-3. DOI: 10.1038/nchem.2697 

 

 

169 Twisting the Ethano-Tröger’s Base: The Bisamide 
Cvengros J, Pereira R, Pfeifer L, Fournier J, Gouverneur V
Org. Biomol. Chem. 2017, 15, 628-633. DOI: 10.1039/C6OB02359B