Véronique Gouverneur Research

Department of Chemistry University of Oxford

August 2020

Our recent paper 'Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery' was highlighted in OPRD as an 'item of interest to process R&D chemists and engineers.

July 2020

UNIQ 2020: Alongside other Oxford chemists VG group member Joseph Ford was involved in the development and delivery of a kitchen chemistry workshop, based on the chemistry of turmeric. Joe helped deliver a session on chirality to the year 12s and provided support to the students in the online forum. It was a unique UNIQ experience this year, with the Department delivering a remote academic programme via Teams. Well done Joe!

Francesco Ibba has been named as one of the 45 finalists of the Reaxys PhD Prize 2020. Congratulations!

Congratulations to VG group members Giulia, David, Francesco, Anna and Gabriele for the publication: Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ-Fluoroamines

May 2020

Congratulations to VG group members Jeroen Sap  & Claudio Meyer for the publication: Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery

April 2020

Congratulations to FLUDD ESRs- Sandrine Hell and Claudio Meyer and VG Group member Jeroen Sap for the publication in Angewandte Chemie: Hydrosulfonylation of Alkenes with Sulfonyl Chlorides under Visible Light Activation

Congratulations to Florian Guibbal for the publication in Molecular Imaging and Biology: [18F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging

March 2020

Jeroen Sap has been awarded an EPSRC Doctoral Prize Award. Congratulations!

Congratulations to VG group members Florian Guibbal & Jeroen Sap for the publication in Nature Protocols: Manual and automated Cu-mediated radiosynthesis of the PARP inhibitor [18F]olaparib

February 2020

Congratulations to Jeroen Sap for winning the RSC Medicinal Chemistry Poster Prize at the RSC meeting: Applied Late-Stage Functionalisation: Where Chemistry Meets Biology, Manchester (UK).

January 2020

Congratulations to VG group members Osman Tack, Florian Guibbal, Adeline W. J. Poh for the publication: 18F-Trifluoromethanesulfinate enables Direct C–H 18F-Trifluoromethylation of Native Aromatic Residues in Peptides

December 2019

Congratulations to FLUDD ESRs Claudio Meyer and Sandrine Hell for the publication: Silyl Radical-Mediated Activation of Sulfamoyl Chlorides Enables Direct Access to Aliphatic Sulfonamides from Alkenes

Francesco presented a poster (Title: Hydrogen Bonding Phase ​Transfer Catalysis: Reaction Discovery and Mechanistic Insights) of his research at the Sciupdate 26th Annual Review Meeting “Catalysis and Enabling Technologies for Synthesis”, Belgrave Square, London. Well done!

November 2019

Congratulations to Anna Vicini who has been selected as one of the winners of the Scientific Update 'Young Chemist Award'.

October 2019

Congratulations to the Gouverneur Group- the Gouverneur fluorination catalyst is now commercially available!

September 2019

An interview with Veronique! ''How working outside your research specialty can lead to “a fantastic journey”.

Congratulations to Anna Vicini for winning a prize for one of the best oral communication at the 3rd international Symposium on Synthesis and Catalysis (ISySyCat 2019) Evora, Portugal.

The 2nd FLUDD School took place this month in Toledo, Spain.

July 2019

Anna presented a poster of her research at the 26th Internation Symposium : Synthesis in organic chemistry. See Anna in action. Well done!

Chalk Talks! Post Doc Matthew Horwitz gave a 5 minute bitesize talk with the aid of only a board and chalk at this OxSci event.

June 2019                                                                                                                                                                                       

The group BBQ in the sun!

May 2019

Congratulations to Anna Vicini for winning a poster prize at the Chem East Symposium.

Many Congratulations to Anna, David, Francesco and Gabriele. Their recently published article (Hydrogen Bonding Phase-Transfer Catalysis with Potassium Fluoride: Enantioselective Synthesis of β-Fluoroamines) has been selected by the Editorial Board of SYNFACTS for its important insights as “SYNFACTS of the month.

The Gouverneur Group are now featured on the Merck (Sigma-Aldrich) Professor Product Portal.

PhD Student Anna Vicini 'Tech me Out' event manager at this years Pint of Science Event, Oxford.  

April 2019

Congratulations to FLUDD ESRs Claudio Meyer and Sandrine Hell for the publication: Hydrodifluoromethylation of Alkenes with Difluoroacetic Acid

Well done to Anna & Francesco for presenting their current research at the 18th Annual RSC Fluorine Subject Group Postgraduate Meeting.                           

March 2019

Massive congratulations to Veronique for securing an ERC Advanced Grant to explore new avenues in Phase Transfer Catalysis.

23rd March 2019.....PhD Student Anna Vicini took science to the public at the ATOM festival in Abingdon.

12th March 2019.....Post Doc Matthew Horwitz gave an academic taster lecture entitled 'Phosphorus in Organic Catalysts' to 44 GCSE students.

Together with ESRs from the Ben Davis Group, members of the Gouverneur group organised and hosted the

 5th ISOTOPICS training event in the NEW Chemistry Teaching Laboratorym University of Oxford.

February 2019

Congratulations to Robert Szpera, Daniel Moseley, Lewis Smith and Alistair Sterling for the publication of this review.....

The fluorination of C–H bonds: developments and perspectives

January 2019

THREE New publications from the group! CONGRATULATIONS!

Synthesis and Reactivity of a-Cumyl Bromodifluoromethanesulfenate: Application to the Radiosynthesis of [18F]ArylSCF3

Synthesis of 18F-Difluoromethylarenes Using Aryl Boronic Acids, Ethyl bromofluoroacetate and [18F]Fluoride

Hydrogen Bonding Phase-Transfer Catalysis with Potassium Fluoride: Enantioselective Synthesis of β-Fluoroamines

Celebrating 2 publications in Tetrahedron! welldone.

Data-mining the diaryl(thio)urea conformational landscape: Understanding the contrasting behavior of ureas and thioureas with quantum chemistry

Enantioselective rhodium-catalysed insertion of trifluorodiazoethanes into tin hydrides

November 2018

Well done to Gabriele for presenting  his current research in a poster entitled 'Hydrogen Bonding Phase-Transfer Catalysis (HB-PTC) for Asymmetric Nucleophilic Fluorinations' at IKCOC-14

Welcome to our new post docs! Alexander Durr, Florian Guibbal and Matthew Horwitz.

New Publication! PET imaging of PARP expression using [18F]olaparib.....................Congratulations!

October 2018

Congratulations to Rob Szpera for winning the Alan Howe prize for best junior lab demonstrator!

September 2018

Veronique presents at the 22-ICOS conference in Florence.

August 2018

Well done to Gabriele for presenting his current research at the 7th EuChemS Chemistry Congress.

Congratulations to the group on the publication of the recent review on the use of boron reagents for divergent radiochemistry!

Well done to David Ascough & Francesco Ibba who presented their current research at this years ACS in Boston.

Veronique hosts to EuChemS YIW 2018 at Merton College, Oxford. Thank you to group members Jeroen and Zijun for all your help over the two day meeting.

July 2018

Well done to Kee, David, Francesco, Tom & Gabriele who presented their current research at the ISFC 2018.

June 2018

Well done to David Ascough & Francesco Ibba who presented their current research at this years Oxford Summer Synthesis Conference.

May 2018

Congratulations on the publication of Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis, in Science!

April 2018

Marie Curious! ISOTOPICS ESR Anna Vicini participated in this STEM event.

Welcome Laura Trump, a visiting Early Stage Researcher from UCB.

March 2018

Talking Careers at the Chemistry Careers Conference- Manuja speaks of her experience as a Project Manager in the Gouverneur Group.

Veronique speaks about 'Fabulous Fluorine' –part of the Oxford International Women’s festival, The Dorothy Hodgkin Memorial Lecture

FLUDD ESR Tim has started his first Industrial Placement at Janssen NV, Beerse.

February 2018

Welcome Maxime Ghosez, visiting us on an Erasmus program from the Faculty of Sciences of the University of Namur (UNamur, Belgium).

Veronique delivered a research seminar entitled Late Stage Fluorination for PET Imaging at the Department of Chemistry, University of Hull.

Congratulations to Jeroen Sap and David Ascough for winning Eli Lilly prizes for Excellence in Organic Chemistry Research. 

Congratulations to Jeroen Sap for winning the poster prize at the SCI event (Organofluorine Chemistry: Synthetic Methods and Applications), held in London.

FLUDD ESRs Sandrine and Claudio have started their first Industrial Placement at Janssen CILAG, Spain.

October 2017

Congratulations to Stephen Hyde for winning a presentation prize at the AstraZeneca-sponsored Final Year DPhil Symposium.

September 2017

Congratulations to Stephen Hyde for winning an oral presentation prize at the 17th Annual RSC Fluorine Subject Group Postgraduate Meeting, held at the University of Leicester.

Congratulation to Thomas Wilson for winning a poster prize at the 6th UKPET Chemistry Conference held in Hull.

Congratulations to Jeroen Sap for winning an poster presentation prize at the 17th Annual RSC Fluorine Subject Group Postgraduate Meeting, held at the University of Leicester.

July 2017

Congratulations to Veronique on being elected a member of the European Academy of Sciences 

January 2017

Congratulations to Lukas Pfeifer on passing his viva

Redox chemistry of trifluoromethyl sulfonium salts as CF3 radical sources awarded top 5 highly cited paper in Journal of Fluorine Chemistry.

http://users.ox.ac.uk/~vgweb/highly_cited_paper_jan_2017.jpg

Old Group News

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Gallery

Jeroen Sap (RSC meeting: Applied Late-stage Functionalisation: Where Chemistry meets Biology, University of Manchester)

Wilston T et al 2018

Francesco Ibba (Oxford Synthesis Summer Conference, University of Oxford)

Gouverneur Group research published in Science.

David Ascough (Eli Lilly prizes for Excellence in Organic Chemistry Research, University of Oxford)

Jeroen Sap (Eli Lilly prize for Excellence in Organic Chemistry Research, University of Oxford)

http://users.ox.ac.uk/~vgweb/group_news_photos/HydeLeicester.JPG

Stephen Hyde (Oral presentation prize, 17th Annual RSC Fluorine Subject Group Postgraduate Meeting,University of Leicester)

http://users.ox.ac.uk/~vgweb/group_news_photos/TomHull.jpg

Thomas Wilson (Poster prize, 6th UKPET Chemistry Conference, Hull)